"The mind of man plans his way, But the Lord directs his steps." -Solomon
In a culture busy about making plans, being a success, accomplishing something....being significant...whatever that means, the Bible invites us to sit in the back seat and let God oversee all of that. In other words you need to know God's not interested in you being significant...he's interested in you finding your significance in HIM.
Our plans, our successes, our accomplishments are only of value when we surrender them and turn them over to God. It's only when we are no longer interested in "making a difference" that we really will.
There is a wonderful book that puts this in perspective. It's one every Christ follower should read. It's titled, "Embracing Obscurity" and it deals with the conflict between God and culture, between success in this world and in eternity.
Making a difference really has nothing to do with what you do, but everything to do with who does it. It's a fascinating discussion I will be continuing in the days ahead, but for today this is more than enough to challenge your perception of reality and what really matters.